Author

Saumya R. Udagedara

La Trobe University

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Jie Qi HuangiD· 1 shared Jing Zhi Anson TaniD· 1 shared Jocelyn WidagdoiD· 1 shared Lara NeureiteriD· 1 shared Mihwa LeeiD· 1 shared Nishita BhembreiD· 1 shared Victor AnggonoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Jie Qi HuangORCID

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1 paper

Recent·Most cited

NeuroscienceOpen BiologyPeer-reviewedSep 1, 2022

Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates that reduce surface AMPA receptor expression in primary neurons

Jocelyn Widagdo, Saumya R. Udagedara, Nishita Bhembre…·Mihwa Lee

This study shows that ALS-linked SFPQ mutations increase zinc binding and cytoplasmic aggregation, reducing surface AMPA receptor subunit GluA1 in neurons.

20 citations

humanproteomics

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