Author

Mihwa Lee

La Trobe UniversityORCID 0000-0003-3006-2483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Jocelyn WidagdoiD· 2 shared Victor AnggonoiD· 2 shared Andrew C. MarshalliD· 1 shared Anthony A. HymaniD· 1 shared Archa H. FoxiD· 1 shared Charles S. BondiD· 1 shared Jerry CumminsiD· 1 shared Jie Qi HuangiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Jocelyn WidagdoORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Molecular BiologyPeer-reviewedNov 10, 2023

Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates

Andrew C. Marshall, Jerry Cummins, Simon Kobelke…·Mihwa Lee

This study identifies distinct roles of low-complexity regions in SFPQ for biomolecular condensate formation, showing the C-terminal region drives condensation while the N-terminal region inhibits it.

24 citations

humanprotein structure

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NeuroscienceOpen BiologyPeer-reviewedSep 1, 2022

Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates that reduce surface AMPA receptor expression in primary neurons

Jocelyn Widagdo, Saumya R. Udagedara, Nishita Bhembre…·Mihwa Lee

This study shows that ALS-linked SFPQ mutations increase zinc binding and cytoplasmic aggregation, reducing surface AMPA receptor subunit GluA1 in neurons.

20 citations

humanproteomics

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