NR0B1 alters the 9-cis-retinoic acid response in Ewing Sarcoma cells
Benjamin D. Sunkel, Meng Wang, Rachel D. Dreher, Melissa C. Sammons, Lindsay Ryan, Amy C. Gross, Scott Friedland, Ryan David Roberts, Emily R. Theisen, Elaine R. Mardis, Richard K. Wilson
This study shows NR0B1 alters the 9-cis-retinoic acid response in Ewing Sarcoma cells by modulating nuclear receptor activity, suggesting NR0B1 inhibition could enhance retinoid therapy.
bioRxiv · Sep 29, 2025 · PreprintCancer Biology