Intrinsic coordination of dynamic molecular signatures shape the human prefrontal cortex
Patricia R. Nano, Daniel C. Jaklic, Vanna Giang, J Soto, Jessenya Mil, Sean Wang, Antoni Andreu Martija, Brittney D Wick, Maximilian Haeussler, Aparna Bhaduri
The paper identifies YBX1 as a key transcription factor in shaping human prefrontal cortex molecular identity through CRISPR activation screens and organoid experiments.
bioRxiv · May 14, 2026 · PreprintNeuroscience