Claudia V. Nguyen

This study shows that glutamatergic neuron-tumor synapses influence glioblastoma cell states by modulating radial glia plasticity and transcriptional programs.

This study shows thalamic NRXN1 signaling promotes human cortical upper-layer neurogenesis by interacting with outer radial glia.

The paper integrates seven single-cell transcriptomic datasets to generate 225 meta-modules, identifying key gene networks involved in human cortical cell subtype specification and validating their roles in neurodevelopment.

The paper identifies the pentose phosphate pathway's role in regulating radial glia cell fate during human cortical development using metabolic assays and genetic manipulations.

CaPTure is a scalable pipeline for analyzing calcium imaging data from cultured neurons, enabling high-throughput phenotypic discovery.

This study identifies the basolateral amygdala to lateral septum circuit as critical for regulating sociability in mice through BDNF-TrkB signaling.

The paper identifies differentially expressed genes in PTSD and MDD across brain regions, highlighting shared and unique transcriptional patterns and immune-related pathways.

The paper identifies electrophysiological measures in hiPSC-derived neurons linked to schizophrenia diagnosis and cognitive performance.