Systemic MIF facilitates chronic lymphocytic leukemia development independent of its cellular source
Viktoria Kohlhas, Nina Reinart, Natascha Rosen, Sebastian Reinartz, Alexandra Florin, Thanh Tung Truong, Luca D Schreurs, Phuong‐Hien Nguyen, Michael J. Hallek
This study shows that systemic MIF is critical for CLL development, regardless of its cellular source, as Mif-deficient hosts resist disease despite adaptive transfer of CLL cells.
Journal of Leukocyte Biology · Nov 28, 2025Peer-reviewedCancer Biology