Author

Alexandra Florin

University Hospital CologneORCID 0000-0002-2330-4176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Michael J. HallekiD· 2 shared Anna C. BeielsteiniD· 1 shared Astrid C SchaussiD· 1 shared Christian JüngstiD· 1 shared Christian Philipp PallaschiD· 1 shared Jing ZhangiD· 1 shared Jörn MeineliD· 1 shared Linda Müller· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Michael J. HallekORCID

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2 papers

Recent·Most cited

Systemic MIF facilitates chronic lymphocytic leukemia development independent of its cellular source

Viktoria Kohlhas, Nina Reinart, Natascha Rosen, Sebastian Reinartz, Alexandra Florin, Thanh Tung Truong, Luca D Schreurs, Phuong‐Hien Nguyen, Michael J. Hallek

This study shows that systemic MIF is critical for CLL development, regardless of its cellular source, as Mif-deficient hosts resist disease despite adaptive transfer of CLL cells.

Journal of Leukocyte Biology · Nov 28, 2025Peer-reviewedCancer Biology

Focal adhesion pathway inhibition is the central axis of macrophage phenotypic responses to monoclonal antibody therapy in aggressive lymphoma via high-throughput screening and high-content imaging

Stuart James Blakemore, Peter Zentis, Linda Müller, Reinhild Brinker, Michael Michalik, Christian Jüngst, Anna C. Beielstein, Jing Zhang, René Neuhaus, Alexandra Florin, Michael J. Hallek, Jörn Meinel, Reinhard Buettner, Astrid C Schauss, Christian Philipp Pallasch

This study identifies focal adhesion pathway inhibition as a key mechanism enhancing macrophage phagocytosis and improving anti-CD20 monoclonal antibody therapy in aggressive lymphoma through high-throughput screening and high-content imaging.

bioRxiv · Sep 23, 2025 · PreprintCell Biology