Author

Sebastian Zeltzer

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Felicia D. GoodrumiD· 3 shared Carly A. BobakiD· 2 shared Giovanni BoscoiD· 2 shared Marek SvobodaiD· 2 shared Olivia Daigle· 2 shared Pierce LongmireiD· 2 shared Ethan Carpenter· 1 shared Iliyana MikelliD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Felicia D. GoodrumORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity

Pierce Longmire, Sebastian Zeltzer, Kristen Zarrella, Olivia Daigle, Marek Svoboda, Justin M. Reitsma, Scott S. Terhune, Carly A. Bobak, Giovanni Bosco, Felicia D. Goodrum

This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.

Nucleic Acids Research · Dec 5, 2025Peer-reviewedMicrobiology

Complex roles for proliferating cell nuclear antigen in human cytomegalovirus replication

Pierce Longmire, Olivia Daigle, Sebastian Zeltzer, Matias Lee, Marek Svoboda, Marco Padilla‐Rodriguez, Carly A. Bobak, Giovanni Bosco, Felicia D. Goodrum

This study investigates the role of PCNA in HCMV replication, finding it restricts virus replication and contributes to genome diversity through separable PCNA-dependent and -independent mechanisms.

bioRxiv · Jan 6, 2025 · PreprintMicrobiology

EGR1 transcriptional control of human cytomegalovirus latency

Jason Buehler, Ethan Carpenter, Sebastian Zeltzer, Suzu Igarashi, Michael A. Rak, Iliyana Mikell, Jay A. Nelson, Felicia D. Goodrum

This study identifies EGR1 as a key transcription factor regulated by EGFR signaling that promotes CMV latency by enhancing UL138 expression in CD34+ HPCs.

bioRxiv · May 24, 2019 · PreprintMolecular Biology