Giovanni Bosco

This study identifies host DNA repair factors that enable antiviral nucleoside analog resistance by facilitating viral DNA synthesis in the presence of ganciclovir.

This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.

This study investigates the role of PCNA in HCMV replication, finding it restricts virus replication and contributes to genome diversity through separable PCNA-dependent and -independent mechanisms.

The paper identifies and mitigates the effects of internal oligo(dT) priming in bulk and single cell RNA sequencing, improving gene expression measurement.

The paper uses scRNA-seq to study gene expression changes in conditional Pten knockout mouse neurons, identifying altered gene expression patterns.

This paper demonstrates a method to use CaMPARI to label active neurons in freely-moving adult fruit flies during a stimulus.

The paper shows that maternal repression of NPF in Drosophila leads to transgenerational inheritance of ethanol preference through germline caspase activation.

This study identifies six brain regions and specific neuron subgroups in Drosophila essential for dialect learning through social interactions.

The paper identifies 11 novel Drosophila genes involved in long-term memory formation using computational methods and behavioral assays.

This study shows that Drosophila species can learn to communicate threats through visual and olfactory signals, enhancing interspecies communication after cohabitation.

The paper uses machine learning to identify Drosophila Grunge/Atrophin as a gene critical for memory retention and social learning.