Author
AbbVie (United States)ORCID 0000-0002-2700-6440Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Pierce Longmire, Sebastian Zeltzer, Kristen Zarrella…·Felicia D. Goodrum
This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.
Ines Forrest, Louis Patrick Conway, Clara Gathmann…·Christopher G. Parker
The paper introduces AgnoTACs, bifunctional molecules that enable proteome-wide discovery of degradable proteins, identifying over 50 previously untargeted proteins.
Yunan Zheng, Anamika Singh, Zeqi Niu…·Ryan A. Mehl
This paper introduces an in-cell method to evaluate E3 ligases for targeted protein degradation by conjugating neo-substrates via click chemistry.
Ananya A. Basu, Chenlu Zhang, Milad Rouhimoghadam…·Xiaoyu Zhang
This study shows that the FBXW7 R465C somatic mutant can be used for targeted protein degradation via heterobifunctional compounds.