Author

Pierce Longmire

University of ArizonaORCID 0000-0001-8875-6053Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Carly A. BobakiD· 3 shared Felicia D. GoodrumiD· 3 shared Giovanni BoscoiD· 3 shared Marek SvobodaiD· 2 shared Olivia Daigle· 2 shared Sebastian Zeltzer· 2 shared David R. McKinzeyiD· 1 shared Donald M. CoeniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Carly A. BobakORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance

Pierce Longmire, Han Chen, David R. McKinzey, Mamata Savanagouder, Noelle N. Kosarek, Jean M. Pesola, Carly A. Bobak, Giovanni Bosco, Goodrum Felicia, Donald M. Coen

This study identifies host DNA repair factors that enable antiviral nucleoside analog resistance by facilitating viral DNA synthesis in the presence of ganciclovir.

Proceedings of the National Academy of Sciences · Aug 17, 2026Peer-reviewedMicrobiology

Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity

Pierce Longmire, Sebastian Zeltzer, Kristen Zarrella, Olivia Daigle, Marek Svoboda, Justin M. Reitsma, Scott S. Terhune, Carly A. Bobak, Giovanni Bosco, Felicia D. Goodrum

This paper identifies UL138 as a viral protein that modulates host DNA repair pathways to maintain viral genome integrity during replication.

Nucleic Acids Research · Dec 5, 2025Peer-reviewedMicrobiology

Complex roles for proliferating cell nuclear antigen in human cytomegalovirus replication

Pierce Longmire, Olivia Daigle, Sebastian Zeltzer, Matias Lee, Marek Svoboda, Marco Padilla‐Rodriguez, Carly A. Bobak, Giovanni Bosco, Felicia D. Goodrum

This study investigates the role of PCNA in HCMV replication, finding it restricts virus replication and contributes to genome diversity through separable PCNA-dependent and -independent mechanisms.

bioRxiv · Jan 6, 2025 · PreprintMicrobiology