Author

Sen Han

Brigham and Women's HospitalPrimary ORCID profile (0000-0003-2437-3322 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Sen HaniD1 paper · Qingdao University

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Guyu Tracy QiniD· 3 shared Zhe LiiD· 3 shared Dongxi XiangiD· 2 shared Dongyi ZhaoiD· 2 shared Roderick Terry BronsoniD· 2 shared Xueqing CheniD· 2 shared Aina He· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

Guyu Tracy QinORCID

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3 papers

Recent·Most cited

RUNX1-deficiency drives immune-active ER+ mammary tumorigenesis through activation of interferon signaling

Sen Han, Dongxi Xiang, Xueqing Chen, Dongyi Zhao, Guyu Tracy Qin, Roderick Terry Bronson, Zhe Li

This study shows that RUNX1 loss in ER+ breast cancer promotes immune-active tumor formation through interferon signaling activation.

bioRxiv · Apr 9, 2026 · PreprintCancer Biology

LSD1 ablation promotes mammary tumor metastasis by attenuating NK cell-mediated anti-tumor immunity

Dongxi Xiang, Sen Han, Aina He, Guyu Tracy Qin, Roderick Terry Bronson, Z Li

This study shows that LSD1 ablation in mammary tumor cells reduces NK cell-mediated anti-tumor immunity, leading to increased lung metastasis.

bioRxiv · Mar 15, 2026 · PreprintCancer Biology

Stromal estrogen signaling regulates fallopian tube homeostasis and cancer initiation via inflammatory pathways

Xueqing Chen, Sen Han, Dongyi Zhao, Guyu Tracy Qin, Zhe Li

This study shows that estrogen receptor signaling in fallopian tube stromal cells maintains epithelial homeostasis by promoting proliferation and ciliated differentiation, but excessive estrogen shifts this niche toward inflammation and stemness, contributing to cancer initiation.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology