Xueqing Chen

This study shows that RUNX1 loss in ER+ breast cancer promotes immune-active tumor formation through interferon signaling activation.

This study shows that estrogen receptor signaling in fallopian tube stromal cells maintains epithelial homeostasis by promoting proliferation and ciliated differentiation, but excessive estrogen shifts this niche toward inflammation and stemness, contributing to cancer initiation.

This study investigates how retinol affects the human skin microbiome and its role in retinol's anti-aging effects using phenomics, metagenomics, and metabolomics.

This study presents genome assemblies of two homosporous lycophytes, revealing preserved gene collinearity and slow genome evolution over 350 million years.

This study presents the haplotype-resolved genome of Ligusticum chuanxiong, identifies enzymes involved in butylphthalide biosynthesis, and reveals its hybrid origin.

This study identifies the role of Notch signaling in repressing cone photoreceptor formation by maintaining multipotent retinal progenitor cells and preventing their transition to restricted progenitor cells.