BAX requires VDAC2 to mediate apoptosis and to limit tumor development
Hui San Chin, Mark F. van Delft, Robert L. Ninnis, Mark X. Li, Iris K. L. Tan, Boris Reljic, Kristen Scicluna, Laura F. Dagley, Jarrod J. Sandow, Gemma L. Kelly, Stephane Chappaz, Seong L. Khaw, Catherine Chang, Andrew Webb, Colin Hockings, , Grant Dewson
This study identifies VDAC2 as essential for BAX-mediated apoptosis and tumor suppression, showing BAX and BAK are differentially regulated.
bioRxiv · Feb 16, 2018 · PreprintCell Biology