Cancer BiologyNAR CancerPeer-reviewed
STN1 upregulation promotes PARPi resistance in BRCA2-deficient cancer cells via replication fork protection and suppression of ssDNA gap formation
Zubair Ahmed Laghari, Na Li, Serdar Gayybov…·Weihang Chai
This study identifies STN1 as a factor promoting PARPi resistance in BRCA2-deficient cancer cells by stabilizing replication forks and reducing ssDNA gaps.
DOI 10.1093/narcan/zcag023