Physiomimetic culture bias durotaxis toward soft environments
Marina Moro-López, Roberto Alonso‐Matilla, Sergi Olive-Palau, Manuel Gómez‐González, Paolo P. Provenzano, Ramón Farré, Jorge Otero, David J. Odde, Raimon Sunyer
This study shows that cell migration direction (durotaxis) can be reversed by culturing cells in soft 3D environments, revealing it is influenced by culture conditions rather than being intrinsic.
bioRxiv · Mar 26, 2026 · PreprintBiophysics