Author

Sergio Grannum

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aditya Sridhar· 1 shared Ioanna MelaiD· 1 shared Joseph E. ChambersiD· 1 shared Laura S. ItzhakiiD· 1 shared Marc de la RocheiD· 1 shared Maria ZacharopoulouiD· 1 shared Siding Qin· 1 shared Zixuan Huo· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Aditya Sridhar

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1 paper

Recent·Most cited

Programmable DNA-peptide nanostructures for multivalent regulation of intracellular signalling

Maria Zacharopoulou, Zoya Cassidy, Siding Qin, Zixuan Huo, Sergio Grannum, Aditya Sridhar, Joseph E. Chambers, Marc de la Roche, Laura S. Itzhaki, Ioanna Mela

This paper develops DNA-peptide nanostructures to multivalently inhibit TNKS, showing they effectively downregulate Wnt signaling in cancer cells despite differences in TBP copy number.

bioRxiv · Sep 9, 2026 · PreprintBiophysics