Structural Basis of CSN-mediated SCF Deneddylation
Shan Ding, Julie A. Clapperton, Märt-Erik Mäeots, Simone Kunzelmann, Mohammed Shaaban, Radoslav Ivanov Enchev
This study uses cryo-EM to reveal structural intermediates of CSN-mediated SCF deneddylation, providing insights into the mechanism and potential for drug design.
Nature Communications · Jan 23, 2026Peer-reviewedBiochemistry