Author

Mohammed Shaaban

The Francis Crick InstituteORCID 0000-0002-4503-0356Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Julie A. ClappertoniD· 1 shared Märt-Erik MäeotsiD· 1 shared Radoslav Ivanov EncheviD· 1 shared Shan Ding· 1 shared Simone KunzelmanniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Julie A. ClappertonORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJan 23, 2026

Structural Basis of CSN-mediated SCF Deneddylation

Shan Ding, Julie A. Clapperton, Märt-Erik Mäeots…·Radoslav Ivanov Enchev

This study uses cryo-EM to reveal structural intermediates of CSN-mediated SCF deneddylation, providing insights into the mechanism and potential for drug design.

2 citations

cryo-EMexperimental assay

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