Spatially patterned, spectral single-molecule microscopy
Joseph S. Beckwith, Brendan Cullinane, Daniel F. Heraghty, Sina Krokowski, Caroline L. Jones, Shengbo Yang, Rebecca C. Gregory, R. Andrés Floto, Yuxuan Zhang, Ana Mafalda Santos, Simon Davis, Michele Vendruscolo, David Klenerman, Viv Lindo, Praveen Kallamvalliillam Sankaran, Steven F. Lee
This paper introduces a new spectral single-molecule microscopy technique using spatially patterned detectors, achieving spectral and positional resolution without complex optical components.
bioRxiv · Aug 28, 2026 · PreprintBiophysics