Author

Shivali Rawat

Centre for Cellular and Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anamika Ghosh· 1 shared Anusha ValpadashiiD· 1 shared Debabani GangulyiD· 1 shared Diwakar Shukla· 1 shared Elizabeth Phillippi· 1 shared Eric Giavedoni· 1 shared Ganesh V. Pusapati· 1 shared K. Sreedurgalakshmi· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Anamika Ghosh

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Tiled base editing screens uncover rare second-site mutations that rescue a misfolded disease protein

Shivali Rawat, Parijat Sarkar, Eric Giavedoni, Ganesh V. Pusapati, Murugesh Padmanarayana, Mallory Shin, Elizabeth Phillippi, Taylar Simmons, Ruth Azaria, Diwakar Shukla, Mark L. Schultz, Rajat Rohatgi

The paper uses base editing screens to identify second-site mutations that correct misfolded NPC1 proteins, enabling therapeutic applications for diseases like Niemann-Pick type C.

bioRxiv · Nov 2, 2026 · PreprintCell Biology

Proteostasis perturbation destabilizes respiratory complex assembly-intermediates via aggregation of subunits

Shivali Rawat, Anusha Valpadashi, Manoranjan Jha, K. Sreedurgalakshmi, Anamika Ghosh, Debabani Ganguly, Swasti Raychaudhuri

The paper shows that proteostasis disruption leads to RCC subunit aggregation, impairing complex assembly and causing mitochondrial dysfunction.

bioRxiv · May 2, 2018 · PreprintMolecular Biology