Identification of chemical features that influence mycomembrane permeation and antitubercular activity
Irene Lepori, Zichen Liu, Nelson Iyore Evbarunegbe, Shasha Feng, Turner P. Brown, Kishor Mane, Shivangi Shivangi, Mitchell Wong, Amir George, Taijie Guo, Jiajia Dong, Joel S. Freundlich, Wonpil Im, Anna G. Green, Marcos M. Pires, M. Sloan Siegrist
The paper identifies chemical features affecting mycomembrane permeation and antitubercular activity using a bioorthogonal assay and machine learning.
bioRxiv · Feb 27, 2025 · PreprintMicrobiology