Zichen Liu

Molecular Determinants Governing the Antitubercular Activity of Griselimycin

This study investigates the structure-activity relationship of griselimycin, identifying key amino acids and modifications that enhance its antitubercular activity.

Profiling Cytosolic Drug Delivery in Mammalian Cells: A Generalizable Assay for Intracellular Accumulation

The paper introduces the CHAMP assay to measure cytosolic drug accumulation in mammalian cells, showing how molecular structure affects penetration.

Identification of chemical features that influence mycomembrane permeation and antitubercular activity

The paper identifies chemical features affecting mycomembrane permeation and antitubercular activity using a bioorthogonal assay and machine learning.