Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors
Fay Cooper, Céline Souilhol, Scott Haston, Shona Gray, Katy Boswell, Antigoni Gogolou, Thomas J.R. Frith, Dylan Stavish, Bethany M. James, Daniel A. Bose, Jacqueline Kim Dale, Anestis Tsakiridis
This study shows Notch signalling promotes mesodermal fate and HOX gene activation in human NMPs while inhibiting neural fate through a feedback loop with FGF.
Development · Jan 15, 2024Peer-reviewedDevelopmental Biology