Delivering mRNAs to mouse tissues using the SEND system
Masato Ohtsuka, Jurai Imafuku, Shuho Hori, Aki Kurosaki, Ayaka Nakamura, Tsubasa Nakahara, Takashi Yahata, Kolari S. Bhat, Steven T. Papastefan, So Nakagawa, Rolen M. Quadros, Hiromi Miura, Channabasavaiah B. Gurumurthy
This study demonstrates the SEND process in vivo using genetically engineered mouse models, showing potential for using SEND-VLPs as a gene therapy tool for delivering mRNAs to tissues.
bioRxiv · Jan 28, 2023 · PreprintGenomics