Author

Zhenfeng Shu

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bo PengiD· 2 shared Pinghui FengiD· 2 shared Quansheng HeiD· 2 shared Shu FengiD· 2 shared Yousheng ShuiD· 2 shared Baozhi Yang· 1 shared Casey CheniD· 1 shared Chao QiniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Bo PengORCID

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Author profile →

4 papers

Recent·Most cited

Bacteria-herpesvirus interaction reveals a proviral role of ISGylation in promoting herpesvirus capsid assembly

Shutong Li, Shu Feng, Yongzhen Liu, Chao Qin, Jianglin Zhang, Takeru Saito, Xinchi Xie, Wen Fu, Rui Wang, Yue Zheng, Zhenfeng Shu, Wayne Wei Yeh, Sean Sasaki, Natalia O. Tjokro, Lin Chen, , Pinghui Feng

This study shows that ISGylation, induced by bacterial co-infection, promotes herpesvirus capsid assembly and replication by modifying viral proteins.

bioRxiv · Jan 20, 2026 · PreprintMicrobiology

HSV-1 infection induces brain cofilin hyperphosphorylation in the 5xFAD Alzheimer's Disease mouse model

Laia Gharavi-naeini, Zhenfeng Shu, Farhang Alem, Shu Feng, Linda D. Chilin, Pinghui Feng, Yuntao Wu

This study shows HSV-1 infection increases cofilin phosphorylation in 5xFAD mice, linking viral infection to AD pathology through actin cytoskeleton disruption.

bioRxiv · Aug 10, 2025 · PreprintMicrobiology

Microglia facilitate and stabilize the response to general anesthesia

Yang He, Taohui Liu, Quansheng He, Wei Ke, Xiaoyu Li, Jinjin Du, Suixin Deng, Zhenfeng Shu, Jialin Snow Wu, Baozhi Yang, Yuqing Wang, Ying Qing Mao, Yanxia Rao, Yousheng Shu, Bo Peng

This study shows that microglia facilitate and stabilize the general anesthesia response by activating P2Y12 and calcium influx, without involving dendritic spine plasticity.

bioRxiv · Oct 6, 2023 · PreprintNeuroscience

Functional autapses form in striatal parvalbumin interneurons but not medium spiny neurons

Xuan Wang, Zhenfeng Shu, Quansheng He, Xiaowen Zhang, Luozheng Li, Xiaoxue Zhang, Liang Li, Yujie Xiao, Bo Peng, Feifan Guo, Da-Hui Wang, Yousheng Shu

The paper identifies functional autapses in striatal parvalbumin interneurons but not in medium spiny neurons through electrophysiological recordings and simulations.

bioRxiv · Apr 1, 2022 · PreprintNeuroscience