A dWDR45 knock-out Drosophila model to decipher the role of autophagy in BPAN
Marion Celle, Sahra Aniorte, Abdul-Raouf Issa, Marion Falabrègue, Haixiu Jin, Irene Sanchez-Mirasierra, Shuzhe Ding, Sandra‐Fausia Soukup, Laurent Seugnet, Lujian Liao, Gaëtan Lesca, Ludivine Walter, Bertrand Mollereau
This study generates a dWDR45 knock-out Drosophila model to investigate autophagy's role in BPAN, finding that autophagy defects contribute to some but not all phenotypes.
Human Molecular Genetics · Dec 22, 2025Peer-reviewedCell Biology