Sidharth Goel

A gene expression atlas of a juvenile nervous system

This study creates a gene expression atlas of C. elegans L1 neurons, identifying differentially expressed genes and regulatory networks involved in postembryonic neurogenesis and maturation.

precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions

The paper evaluates variant calling in difficult genomic regions using short- and long-read sequencing, showing improved performance with new methods and multi-technology approaches.

Haplotype-aware variant calling enables high accuracy in nanopore long-reads using deep neural networks

The paper introduces a haplotype-aware variant calling pipeline for nanopore and PacBio HiFi data, achieving high accuracy in variant detection and de novo assembly polishing.

DeepTrio: Variant Calling in Families Using Deep Learning

DeepTrio improves variant calling in family trios using deep learning, achieving higher accuracy than DeepVariant, especially at lower coverages.

Improving variant calling using population data and deep learning

This study improves variant calling by integrating population data into deep learning models, enhancing precision and recall across diverse populations.

An Extensive Sequence Dataset of Gold-Standard Samples for Benchmarking and Development

The paper provides a dataset of 9 gold-standard samples sequenced on multiple platforms and protocols to benchmark sequencing and analysis methods.