Alexis Weinreb

The paper identifies a novel mechanism for synaptic localization of an AChR through direct interaction with IgLON adhesion molecules in C. elegans.

This study creates a gene expression atlas of C. elegans L1 neurons, identifying differentially expressed genes and regulatory networks involved in postembryonic neurogenesis and maturation.

The paper shows that muscle activity influences axon termination in C. elegans SAB neurons through retrograde signals and calcium dynamics.

The paper identifies oscillatory gene expression in specific cell types using single-cell RNA sequencing and computational methods, finding that cuticle-producing cells exhibit oscillatory patterns while neurons and muscle do not.

CellSpliceNet predicts alternative splicing outcomes in C. elegans neurons by integrating multiple data modalities and achieving high predictive accuracy.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper presents an atlas of alternative splicing in C. elegans neurons, identifies novel splicing events, and describes regulatory patterns and networks.

The paper generates a draft connectome of neuropeptide signaling in C. elegans by integrating single-cell data with biochemical analysis.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper provides a comprehensive gene expression profile of all 302 neurons in the C. elegans nervous system and identifies cis-regulatory elements and adhesion proteins involved in synaptic specificity.

The paper compares two RNA-seq library preparation methods for C. elegans, finding that SoLo Ovation with a custom rRNA depletion kit improves detection of noncoding RNAs and reduces noise in lowly expressed genes.

Transcriptomes of 52,412 neurons resolve 109 of the 118 canonical hermaphrodite neuron classes, and neuropeptide genes separate subtypes inside individual classes.