David M. Miller

The paper identifies FMIL-1 as a gene that directs synapse formation in a C. elegans nociceptive circuit by promoting connectivity between PVD neurons and PVC/AVA interneurons.

The paper identifies both cell-autonomous and non-cell-autonomous roles of UNC-3 in C. elegans motor neurons, revealing its impact on neuronal identity and downstream connectivity.

This study creates a gene expression atlas of C. elegans L1 neurons, identifying differentially expressed genes and regulatory networks involved in postembryonic neurogenesis and maturation.

CellSpliceNet predicts alternative splicing outcomes in C. elegans neurons by integrating multiple data modalities and achieving high predictive accuracy.

This study identifies a role for FKH-7/FOXP in chemosensory neurons regulating developmental decision-making and links it to autism-associated gene variants.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper presents an atlas of alternative splicing in C. elegans neurons, identifies novel splicing events, and describes regulatory patterns and networks.

The paper shows that UNC-8, an ENaC protein, promotes Ca2+-dependent endocytosis to dismantle and recycle presynaptic components during neuronal remodeling in C. elegans.

The paper creates a molecular atlas of adult C. elegans motor neurons, identifying 29 subclasses defined by transcription factor and neuropeptide codes, and shows conservation between C. elegans and mice.

The paper integrates bulk and single-cell RNA-seq data from C. elegans neurons to improve transcript detection and differential gene analysis.

The paper identifies ETR-1/CELF1 RNA targets in C. elegans body wall muscle, revealing roles in muscle physiology and neuronal migration.

The paper shows cAMP signaling directs gap junction trafficking to assemble and position electrical synapses in C. elegans motor neurons.

The paper provides a comprehensive gene expression profile of all 302 neurons in the C. elegans nervous system and identifies cis-regulatory elements and adhesion proteins involved in synaptic specificity.

The paper identifies a transcriptional pathway regulated by IRX-1 that drives the removal of presynaptic proteins during neuronal remodeling in C. elegans.

The paper compares two RNA-seq library preparation methods for C. elegans, finding that SoLo Ovation with a custom rRNA depletion kit improves detection of noncoding RNAs and reduces noise in lowly expressed genes.

The paper identifies EGFR signaling in the RIS neuron and its indirect activation via the ALA neuron as mechanisms for sleep induction following cellular stress in C. elegans.

Transcriptomes of 52,412 neurons resolve 109 of the 118 canonical hermaphrodite neuron classes, and neuropeptide genes separate subtypes inside individual classes.

The paper identifies actin assembly and non-muscle myosin activity as drivers of dendrite retraction in a UNC-6/Netrin-dependent self-avoidance response in C. elegans.

The paper identifies functional dendritic spines in C. elegans GABAergic motor neurons and describes their structural and functional characteristics.

The paper identifies a neuroendocrine neuron, RID, in C. elegans that sustains forward movement through the neuropeptide FLP-14.