Intergenerational control of ribosomes under dietary restriction
Sigma Pradhan, Klement Stojanovski, Joel Tuomaala, Nicholas Stroustrup, Benjamin D. Towbin
The paper shows that maternal dietary restriction reduces offspring ribosome content in C. elegans, mediated by mTORC1 signaling, delaying growth until ribosomal levels recover.
bioRxiv · Mar 1, 2025 · PreprintPhysiology