Author

Joel Tuomaala

University of BernORCID 0000-0002-0646-7029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Benjamin D. TowbiniD· 2 shared Klement Stojanovski· 2 shared Nicholas StroustrupiD· 2 shared Devanarayanan Siva SankariD· 1 shared Jörn DengjeliD· 1 shared Julie Perey· 1 shared Sacha PsalmoniD· 1 shared Sigma Pradhan· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

Benjamin D. TowbinORCID

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2 papers

Recent·Most cited

Intergenerational control of ribosomes under dietary restriction

Sigma Pradhan, Klement Stojanovski, Joel Tuomaala, Nicholas Stroustrup, Benjamin D. Towbin

The paper shows that maternal dietary restriction reduces offspring ribosome content in C. elegans, mediated by mTORC1 signaling, delaying growth until ribosomal levels recover.

bioRxiv · Mar 1, 2025 · PreprintPhysiology

Autophagy-dependent proteome remodelling and ribosome decline balance starvation survival and recovery speed in C. elegans

Joel Tuomaala, Devanarayanan Siva Sankar, Julie Perey, Sacha Psalmon, Klement Stojanovski, Nicholas Stroustrup, Jörn Dengjel, Benjamin D. Towbin

This study shows that autophagy-dependent loss of ribosomal proteins during starvation in C. elegans balances survival and recovery speed by affecting growth resumption.

bioRxiv · Aug 28, 2024 · PreprintPhysiology