Author

Silke Lüschen

University Hospital Schleswig-Holstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Andreas TholeyiD· 1 shared Burkhardt FlemeriD· 1 shared Christoph KaletaiD· 1 shared Christoph RöckeniD· 1 shared Felix SommeriD· 1 shared Fenja Amrei Schuran· 1 shared Jan RuppiD· 1 shared Jerome Genth· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andreas TholeyORCID

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1 paper

Recent·Most cited

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice

Lea Järke, Saskia Weber‐Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen, Christoph Röcken, Andreas Tholey, Christoph Kaleta, Jan Rupp, Philip C Rosenstiel, Felix Sommer

This study shows that deleting HKDC1 in intestinal epithelial cells reduces tumor growth and protects against colorectal cancer in mice by impairing mitochondrial function and cell proliferation.

癌症：英文版 · Mar 20, 2025Peer-reviewedCancer Biology