Author

Consiglia Pacelli

University of FoggiaORCID 0000-0003-4915-5823Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Charles DucrotiD· 2 shared Louis‐Éric TrudeauiD· 2 shared Alex TchungiD· 1 shared Anaïs BrassieriD· 1 shared Aristide Ferrante· 1 shared Benoît Delignat‐LavaudiD· 1 shared Christine Jenny· 1 shared Cláudia PiccoliiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Charles DucrotORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 9, 2025

Loss of neurexins disrupts inhibitory connectivity and increases vulnerability of dopamine neurons in culture

Charles Ducrot, Alex Tchung, Samuel Burke…·Louis‐Éric Trudeau

This study shows that loss of neurexins in dopamine neurons disrupts inhibitory synapse formation and reduces neuronal survival in culture.

DOI 10.64898/2025.12.05.692551

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyCommunications MedicinePeer-reviewedApr 11, 2025

Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer.

Marine Laurent, Rim Harb, Christine Jenny…·Mario Amendola

The paper develops a liver-targeted gene therapy using recombinant AAV8 to cure Lysosomal acid lipase deficiency by correcting lipid accumulation and normalizing gene expression and mitochondrial function in a mouse model.

11 citationstop 3%

mousebulk RNA-seq

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NeuroscienceeLifePeer-reviewedJul 6, 2023

Neurexins Regulate GABA Co-release by Dopamine Neurons

Charles Ducrot, Gregory de Carvalho, Benoît Delignat‐Lavaud…·Louis‐Éric Trudeau

This study shows that neurexins regulate dopamine neuron connectivity and neurotransmission by affecting dopamine reuptake and GABA co-release.

21 citations

mouseexperimental assay

𝕏 PostBluesky