Author
National Institutes of Health
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Simone M. Giovanetti, Meru J. Sadhu
The paper constructs combinatorial RBD mosaics of SARS-CoV-2 and RaTG13 to identify residue-level differences affecting ACE2 binding affinity.
bioRxiv · Oct 20, 2026 · PreprintGenetics
Molly Monge, Simone M. Giovanetti, Apoorva Ravishankar, Meru J. Sadhu
The paper introduces a barcode-based method to track combinatorial genotypes in pooled experiments, enabling high-throughput genetic screening and analysis of complex genotype-phenotype relationships.
G3 Genes Genomes Genetics · Jul 14, 2025Peer-reviewedGenetics
Annette B. Iturralde, Cory A. Weller, Simone M. Giovanetti, Meru J. Sadhu
The paper develops a high-throughput method to identify essential and dispensable domains in AcrIIA4 by generating and testing precise deletions, revealing that PAM binding inhibition is key while catalytic domain interaction is dispensable.
Proceedings of the National Academy of Sciences · Nov 21, 2024Peer-reviewedGenetics
Ilya Andreev, Simone M. Giovanetti, Guillaume Urtecho, Daniel Shriner, Joshua S. Bloom, Meru J. Sadhu
The paper identifies KTD1 as a novel defense factor in Saccharomyces cerevisiae that confers resistance to the K28 killer toxin.
bioRxiv · Oct 25, 2021 · PreprintGenetics