Guillaume Urtecho

This paper develops a culturomics-guided FMT framework that enables stable, antibiotic-independent engraftment by targeting metabolic niches in recipient microbiomes.

This paper develops a metagenome-scale metabolic model to predict FMT outcomes by assessing donor-recipient metabolic compatibility in IBS patients.

MCSPACE infers microbiome spatiotemporal dynamics from co-localization data, showing superior performance over existing methods in mice and human datasets.

SAMPL-seq identifies spatial hubs in the human gut microbiome by sampling micron-scale sub-communities and analyzing microbial co-occurrence across individuals and time.

This study compares the antibody evasion, ACE2 binding, and infectivity of SARS-CoV-2 BA.2.87.1 with EG.5.1 and JN.1, finding BA.2.87.1 has lower immune evasion and reduced infectivity.

The paper identifies KTD1 as a novel defense factor in Saccharomyces cerevisiae that confers resistance to the K28 killer toxin.

The paper profiles 8,269 IPTG-inducible promoters to model gene expression and identify optimal promoter architectures for predictable transcriptional control.

The paper develops a multiplexed assay to study σ70 promoter function in E. coli, finding that sequence elements explain most of the variance in promoter strength.