Author

Sixin Xu

University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 5 Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Approach:deep learning· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:imputation· 1

Frequent Co-Authors

Feifei WangiD· 4 shared Zideng DaiiD· 4 shared Danyang Xu· 2 shared Hanze Yu· 2 shared Hongjie DaiiD· 2 shared Liangqiong QuiD· 2 shared Yuanhua LiuiD· 2 shared Zhisheng WuiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBioengineering

Feifei WangORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Water as a thermal contrast agent for artificial-intelligence-enhanced in vivo mid-infrared thermography

Sixin Xu, Yuanhua Liu, Danyang Xu, Zideng Dai, Wentao Ye, Xingzu Zhan, Feifei Wang

This paper introduces AI-enhanced mid-infrared thermography using cold PBS as a thermal contrast agent to improve in vivo imaging resolution and tumor detection.

bioRxiv · Jul 6, 2026 · PreprintBioengineering

Near-Infrared II Scintillator for High-Resolution X-ray Imaging

Simin Gu, Zhisheng Wu, Sixin Xu, Zideng Dai, Jiajie Zheng, Ai-Min Li, Wallace C. H. Choy, Liangqiong Qu, Hongjie Dai, Feifei Wang

This paper develops an NIR-II scintillator that improves X-ray imaging resolution by reducing light scattering and achieving lower detection limits.

bioRxiv · Jul 2, 2026 · PreprintBiophysics

Focused ultrasound programmed characteristic NIR-IIb lanthanide mechanoluminescence for high sensitivity bioimaging in vivo

Minglong Zhang, Jieying Zhang, Lingkai Meng, Xiaohe Li, Sixin Xu, Xingjun Zhu

This paper develops a FUS-programmed NIR-IIb mechanoluminescent nanoparticle for high-sensitivity in vivo bioimaging with sub-millimeter resolution and low detection limits.

bioRxiv · Dec 31, 2025 · PreprintBioengineering

In vivo Calcium Imaging in the Near-Infrared II Window

Danyang Xu, Zhisheng Wu, Hui Yang, Gu Chen, Wayne Jason Li, Xingyu Yue, Guang-Lei Wang, Sixin Xu, Hanze Yu, Yuanhua Liu, Zideng Dai, Haibo Jiang, Long-Jiang Yu, Hongjie Dai, Feifei Wang

This paper develops a near-infrared II calcium imaging technique using a bacterial protein to enable high-sensitivity, non-invasive deep-tissue calcium imaging in live mammals.

Journal of the American Chemical Society · Dec 24, 2025Peer-reviewedBioengineering

Acoustoluminescence in Transition Metal and Rare Earth Oxides Beyond 1800 nm for In Vivo Imaging

Puxian Xiong, Sixin Xu, Zhexi Liu, Dongsheng Xu, Hanze Yu, Zideng Dai, Zhisheng Wu, Liangqiong Qu, Feifei Wang

This paper demonstrates acoustoluminescence in transition metal and rare earth oxides beyond 1800 nm for in vivo imaging, achieving deeper penetration than fluorescence imaging.

bioRxiv · Dec 7, 2025 · PreprintBioengineering