Yuanhua Liu

This paper introduces AI-enhanced mid-infrared thermography using cold PBS as a thermal contrast agent to improve in vivo imaging resolution and tumor detection.

This paper develops a near-infrared II calcium imaging technique using a bacterial protein to enable high-sensitivity, non-invasive deep-tissue calcium imaging in live mammals.

This paper engineers a TnpB-ωRNA system for efficient gene editing in mice, showing improved activity over Cas12f1 and successful disease prevention in a tyrosinaemia model.

The paper designs high-fidelity Cas13 variants with minimal collateral RNA degradation effects, validated in mammalian cells and transgenic mice.