Author

Siyu Feng

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Bo HuangiD· 2 shared Abhilash BarpandaiD· 1 shared Aidan Winters· 1 shared Arun P. WiitaiD· 1 shared Aruna Varshney· 1 shared Ashutosh MaheshwariiD· 1 shared Audrey KishishitaiD· 1 shared Becky Xu Hua FuiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Bo HuangORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genome-wide CRISPR screens identify PTGES3 as a novel AR modulator

Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Raunak Shrestha, Meng Zhang, Martin Sjöström, Siyu Feng, J. A. Anderson, Wanting Han, Lisa N. Chesner, Hyun Jin Shin, Tatyanah Farsh, Humberto J. Suarez, Seema Nath, Jonathan Chou, , Felix Yi-Chung Feng

This study uses CRISPR screens to identify PTGES3 as a novel modulator of AR protein levels and function in prostate cancer, showing its role in therapy resistance.

Nature Genetics · Nov 5, 2025Peer-reviewedCancer Biology

Bright split red fluorescent proteins with enhanced complementation efficiency for the tagging of endogenous proteins and visualization of synapses

Siyu Feng, Aruna Varshney, Doris Coto Villa, Cyrus Modavi, John Kohler, Fatima Farah, Nebat Ali, Joachim Dieter Mueller, Miri VanHoven, Bo Huang

The paper improves split fluorescent proteins for better brightness and develops a new synaptic marker for visualizing synapses in living animals.

bioRxiv · Oct 25, 2018 · PreprintCell Biology