Author

Siyuan Xu

Shanghai Medical College of Fudan University

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Chuxuan Peng· 1 shared Fei LaniD· 1 shared Jia FaniD· 1 shared Jiabin CaiiD· 1 shared Jianhua Wang· 1 shared Min LuoiD· 1 shared Qin Feng· 1 shared Ruijie GongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Chuxuan Peng

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1 paper

Recent·Most cited

Dual function of DOT1L suppresses tumor intrinsic immunogenicity in hepatocellular carcinoma

Siyuan Xu, Ruijie Gong, Songchen Liu, Jianhua Wang, Yijie Shen, Chuxuan Peng, Qin Feng, Min Luo, Fei Lan, Jia Fan, Jiabin Cai, Xianjiang Lan

The paper identifies DOT1L as a suppressor of tumor intrinsic immunogenicity using CRISPR screens and shows its inhibition enhances immune response in mice.

Oncogene · Mar 30, 2026Peer-reviewedCell Biology