Inhibition of oogenic JNK preserves fertility and ovarian hormones during DNA-damaging cancer therapy
Wenlong Zhao, Jiyang Zhang, Yingnan Bo, Yingzheng Wang, Mi Ran Choi, Shichao Liu, Qiang Zhang, So-Youn Kim, Shuo Xiao
This study shows that inhibiting JNK in oocytes protects against chemotherapy-induced infertility and ovarian hormone loss in mice.
bioRxiv · May 1, 2026 · PreprintPharmacology & Toxicology