Mitochondrial rewiring supports survival of triple negative breast cancer cells after ionizing radiation
Steven W. Wall, Karen Wang, Allison S. Greer, Mokryun L. Baek, Audra Lane, Mariah J. Berner, Jonathan Thomas Lei, Ángel Adrian Garcés, Sofia Khoury, Emily G. Caggiano, Matthew D. Meyer, Sarah Latka, Hugo Villanueva, Emil Schüler, Cullen M. Taniguchi, , Gloria Vittone Echeverria
This study shows that TNBC cells surviving ionizing radiation adopt an OPA1-dependent mitochondrial reprogramming that supports their survival and regrowth.
bioRxiv · Sep 7, 2026 · PreprintCancer Biology