TET1 Catalytic Activity is Required for Reprogramming of Imprinting Control Regions and Patterning of Sperm-Specific Hypomethylated Regions
Rexxi D. Prasasya, Blake A. Caldwell, Zhengfeng Liu, Songze Wu, Nicolae Adrian Leu, Johanna M. Fowler, Steven A. Cincotta, Diana J. Laird, Rahul M. Kohli, Marisa S. Bartolomei
This study shows that TET1's catalytic activity is essential for reprogramming imprinting control regions and sperm-specific hypomethylated regions during germline development.
bioRxiv · Feb 21, 2023 · PreprintDevelopmental Biology