Author

Blake A. Caldwell

University of PennsylvaniaORCID 0000-0002-4263-4058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Diana J. LairdiD· 1 shared Johanna M. FowleriD· 1 shared Marisa S. BartolomeiiD· 1 shared Nicolae Adrian Leu· 1 shared Rahul M. KohliiD· 1 shared Rexxi D. PrasasyaiD· 1 shared Songze Wu· 1 shared Steven A. CincottaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Diana J. LairdORCID

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1 paper

Recent·Most cited

TET1 Catalytic Activity is Required for Reprogramming of Imprinting Control Regions and Patterning of Sperm-Specific Hypomethylated Regions

Rexxi D. Prasasya, Blake A. Caldwell, Zhengfeng Liu, Songze Wu, Nicolae Adrian Leu, Johanna M. Fowler, Steven A. Cincotta, Diana J. Laird, Rahul M. Kohli, Marisa S. Bartolomei

This study shows that TET1's catalytic activity is essential for reprogramming imprinting control regions and sperm-specific hypomethylated regions during germline development.

bioRxiv · Feb 21, 2023 · PreprintDevelopmental Biology