Zhengfeng Liu

This study shows TET1's non-catalytic activity helps maintain chromatin structure to prevent abnormal methylation in male germ cells.

This study shows that in vitro fertilization (IVF) accelerates reproductive aging in female mice by causing premature ovarian failure, with altered ovarian function and epigenetic changes.

This study uses single-nucleus multiomic analysis to reveal PPARA signaling enrichment and metabolic dysfunction in BWS liver.

This study shows that TET1's catalytic activity is essential for reprogramming imprinting control regions and sperm-specific hypomethylated regions during germline development.