Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia
Denise M. Smith, Geetika Aggarwal, Michael L. Niehoff, Spencer A. Jones, Subhashis Banerjee, Susan A. Farr, Andrew D. Nguyen
This study characterizes the GrnR493X mouse model of frontotemporal dementia, finding similar phenotypes to Grn knockout models but with differences in biomarker levels in heterozygous mice.
Molecular Neurobiology · May 2, 2024Peer-reviewedNeuroscience