Structural variants are enriched in deleterious visible phenotypes in Drosophila
Alejandra Samano, Matthew Musat, Mihir Junaghare, Asad Ahmad, Mehlum Ali, Sebastian Alves, Sreeram Pasupuleti, J. Dinithi Perera, Omar Saada, Brady Sabido, Trevor A. Smith, Sophie Walz, Mahul Chakraborty
The paper investigates the role of structural variants in Drosophila phenotypes using long-read sequencing, finding that SVs disproportionately contribute to deleterious visible traits.
Genome Research · May 14, 2026Peer-reviewedGenomics