Norepinephrine is a novel and essential regulator for T-lymphocyte interleukin 17A expression
Tamara Natour, Tatlock H. Lauten, Lauren J. Pitts…·Adam John Case
This study identifies norepinephrine as a novel regulator of T-lymphocyte IL-17A expression through a noncanonical pathway involving TGFβ, cAMP, PKA, CREB, and CBP/p300, distinct from the canonical STAT3-dependent pathway.