A screen for modulation of nucleocapsid protein condensation identifies small molecules with anti-coronavirus activity
Rui Tong Quek, Kierra S. Hardy, Stephen G. Walker, Dan T. Nguyen, Taciani de Almeida Magalhães, Adrian N. Salic, Sujatha M. Gopalakrishnan, Pamela A. Silver, Timothy John Mitchison
The paper identifies small molecules that modulate SARS-CoV-2 nucleocapsid protein condensation and show anti-coronavirus activity across multiple strains.
ACS Chemical Biology · Feb 16, 2023Peer-reviewedMolecular Biology