Stephen G. Walker

This paper shows ganfeborole is a potent time-dependent inhibitor of M. tuberculosis LeuRS with a long post-antibiotic effect, but not effective against E. coli despite inhibiting its LeuRS.

This paper identifies genes that enhance the post-antibiotic effect (PAE) in E. coli using a high-throughput screen of deletion strains, revealing that rfaE deletion increases PAE by stabilizing LpxC.

The paper identifies small molecules that modulate SARS-CoV-2 nucleocapsid protein condensation and show anti-coronavirus activity across multiple strains.